After a PhD training in the Collège de France (Paris) and a post-doc at the Montreal Heart Institute focused on the study of HIF2alpha and its role in angiogenesis, I have been recruited by Inserm in 2007. I now lead a research team at the Paris-Cardiovascular Research Centre of the Georges Pompidou Hospital (HEGP) in Paris dedicated to the study of the genetics and biology of rare cancers, and in particular pheochromocytomas and paragangliomas. our research activity mainly focuses on inherited forms caused by mutations in genes encoding the mitochondrial enzyme sucinate dehydrogenase (SDH) and their role in pseudo-hypoxia, epithelial-to mesenchymal transition and epigenetic modifications.
Academic position
2022: Research Director class 1 (DR1 Inserm) – PARCC-HEGP
019: Team Leader, Inserm team “Genetics and Metabolism of Rare Cancers”
2014-2021: Research Director (DR2 Inserm) – PARCC-HEGP