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Alexandre Loupy Resume’s

Alexandre Loupy

TEAM LEADER : 

 

 

Mail : alexandre.loupy@inserm.fr

 

 

PHONE :+33 1 

 

SCIENTIFIC TOPICS

  • Biology & Biochemistry
  • Molecular Biology & Genetics

ITMO

  • Circulation, métabolisme et nutrition
  • Génétique, génomique et bio informatique

Course and current status

After a PhD training in the Collège de France (Paris) and a post-doc at the Montreal Heart Institute focused on the study of HIF2alpha and its role in angiogenesis, I have been recruited by Inserm in 2007. I now lead a research team at the Paris-Cardiovascular Research Centre of the Georges Pompidou Hospital (HEGP) in Paris dedicated to the study of the genetics and biology of rare cancers, and in particular pheochromocytomas and paragangliomas. our research activity mainly focuses on inherited forms caused by mutations in genes encoding the mitochondrial enzyme sucinate dehydrogenase (SDH) and their role in pseudo-hypoxia, epithelial-to mesenchymal transition and epigenetic modifications.

Academic position

  • 2022: Research Director class 1 (DR1 Inserm) – PARCC-HEGP
  • 019: Team Leader, Inserm team “Genetics and Metabolism of Rare Cancers”
  • 2014-2021: Research Director (DR2 Inserm) – PARCC-HEGP
  • 2014-2018: co-Team Leader– PARCC-HEGP
  • 2011-2014: Senior Researcher (CR1 Inserm) – PARCC-HEGP
  • 2009: Group leader of the “PPGL” laboratory – PARCC-HEGP, Paris
  • 2007-2011: Junior Researcher (CR2 Inserm) – Collège de France and PARCC-HEGP

Participation to scientific committees

  • 2021-now: Head of the PPGL working group of ENS@T
  • 2018-now: Associate Editor at Endocrine-related Cancer
  • 2018-2021: Elected member of the PPGL working group of ENS@T
  • 2017-2021: Member of the Scientific comitee of the French Society of Endocrinology (SFE)
  • 2016-now: Member of INSERM commission CSS2
  • 2015-now: Co-chair of the Pheochromocytoma Research Support Organization (PRESSOR).
  • 2015-now: Member of the “Rare Cancers” working group from the Cancéropôle Ile de France
  • 2010-now: Member of the European Network for the Study of Adrenal Tumors (ENS@T)
  • 2009-now: Co-Chairman of the «Animals models» working group from PRESSOR.

Awards

  • 2002: Young Researchers award (Fondation Bettencourt-Schueller)
  • 2013-now: Prize of Scientific Excellence