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Jean-Sébastien Silvestre

Inserm Research Director (DR1)
TEAM LEADER – REGENERATIVE THERAPIES FOR CARDIAC AND VASCULAR DISEASE
Mail : jean-sebastien.silvestre@inserm.fr
PHONE :+33 1 53 98 80 60


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SCIENTIFIC TOPICS

  • Cardiovascular Disease
  • Heart failure
  • Inflammation
  • Non-cell based therapy

  

ITMO

  • Physiopathologie, métabolisme, nutrition

Biosketch

I obtained my PhD in cardiovascular physiology from the University of Paris 7 in 1998. I was then a research fellow at the Institute of Genetic Medicine, University of South California, (Los Angeles, USA) from 1998 till 1999. In 1999, I started my independent research career as an associate professor (Paris-Diderot university) at the Cardiovascular Research Center Inserm Lariboisière (Paris, France). In 2008, I successfully passed the competitive entrance examinations to the National Institute for Health and Medical Research (INSERM) where I was instantly appointed Research Director. In 2009, I moved to the Paris Cardiovascular Research Center – INSERM UMRS 970 (Paris, France) where I am leading a team working on regenerative therapies for cardiac and vascular disease.

Academic position

  • 2015: Research director (academic professor level), 1st class (top 20%), INSERM, Paris, France
  • 2008-2014: Research director (academic professor level), 2nd class, INSERM, Paris, France
  • 2006-2008: Honorary member (Junior), Institut Universitaire de France, Paris, France
  • 1999-2008: Associate professor, Paris 7 University, Paris, France

 

Responsabilities and activities

  • 2022-present: Deputy director, Paris Cardiovascular Research Center, Inserm / Université Paris Cité
  • 2022-present: Co-director Graduate School Cardiovascular Sciences – Université Paris Cité,

  • 2021-present: Director, Institut des Sciences Cardiovasculaires – Université Paris Cité,

  • 2019-present: Co-director Master 2 cardiovascular biology (BiVATH), Université Paris Cité

  • 2016-2019:  Program Manager for the French National Research Agency – physiology/pathophysiology

  • 2009-present : Director Team 06-PARCC, Paris, France

Awards

  • 2018         Doctoral and Research Supervision award INSERM
  • 2018         Top reviewer award, Arterioscler Thromb Vasc Biol
  • 2017         Jeanne-Philippe Beziat Award, Cardiology, Fondation pour la Recherche Médicale
  • 2014         Award for scientific excellence INSERM
  • 2012         Excellence research chair program, Paris 5 University
  • 2010         Award for scientific excellence INSERM
  • 2007        Excellence research chair program INSERM & Assistance Public – Hôpitaux de Paris
  • 2006        Honorary member – Institut Universitaire de France
  • 2005        French National Research Agency, Young Investigator award
  • 1998         SEARLE young investigator award, Aldosterone conference, New Orleans, USA

Scientific summary

My work focus on the identification of molecular and cellular mechanisms regulating key events in post-ischemic tissue repair with potent revascularization and regenerative therapeutic promise. Since, 1995, I am a co-author of over 100 original research papers and over 40 reviews or book chapters.